New immunotherapy to beat cancer.

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New immunotherapy to beat cancer.  BrinkwireNew immunotherapy to beat cancer  Medical XpressView Full coverage on Google News
Sophie Lucas (University of Louvain de Duve Institute) and her team have succeeded in neutralizing a molecule that blocks the immune system against cancer. The UCLouvain scientists discovered that this new immunotherapy increases the action of another well-known but not always effective immunotherapy, and that it makes tumor regression possible. This very promising discovery in the fight against cancer is published in the journal Nature Communications.

Cancer immunotherapy is the manipulation of the immune responses naturally present in the human body to fight cancer. Often, these immune responses are blocked by cells or molecules that prevent them from killing cancer cells, and the tumor is able to establish itself and grow.

In 2004, Sophie Lucas, researcher at the University of Louvain de Duve Institute, began studying the blocking of immune defenses in tumors in order to understand the functioning of cells that are said to be "immunosuppressive" (which block the body's immune responses). The goal was to identify and remove them, thus stimulating antibodies to act against the tumor. The identified culprits are regulatory T lymphocytes (Tregs): highly immunosuppressive cells in cancer patients. In 2009, Prof. Lucas…
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