New inhaled therapy could treat deadly impacts of asthma

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Scientists have developed an inhaled treatment for asthma that prevents excess mucus from building up in mice.
New inhaled therapy could treat deadly impacts of asthma

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Posted: 14 January 2021 | Victoria Rees (Drug Target Review) |



Scientists have created an inhaled treatment that disrupts the production of excess mucus by reducing disulphide bonds and opening up the airways of mice. The researchers say that this treatment could be used to treat asthma in humans.

The study was conducted at the University of Colorado Anschutz Medical Campus, US.

"Currently about 10 percent of the population has asthma," said the study's lead author Professor Christopher Evans. "Excessive mucus blocks airflow, causing wheezing and worsening the effects of inflammation and contraction of the muscles that line the airways."

The team targeted macromolecules in mucus called polymeric mucin…
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