Chromatin Found to Be a Gel, Which Could Help Explain Cancer's Spread
Chromatin is not a liquid, even though it harbors membraneless liquid-like compartments. Rather, chromatin is a solid-like substance, that is, a gel. Moreover, the liquid-like compartments may be enriched with effector proteins that percolate throughout the fiber matrix, influencing gene expression. Loosening of the gel could account for the ability of cancer cells to squeeze thorough tight spaces during metastasis.