Research: New COVID-19 discovery might predict patient death, hospitalization | Science-Environment

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In a new study, researchers from the University of Copenhagen presented what could be a much-needed helping hand to fight the COVID-19 virus. The study published in the journal EMBO Molecular Medicine, shows that analysis of a particular protein on the cell surface is likely to predict who is in danger of a serious infection caused by the virus, explains Assistant Professor Rajan Gogna, lead author of the new study.
"Cells have a so-called fitness status, and by analyzing it we could predict hospitalization or death in COVID-19 patients, potentially making such a biomarker an earlier prediction tool, especially because it can be detected from the common nasal swap covid-19-tests," says Rajan Gogna from the Won Group at the Biotech Research and Innovation Centre. If the cell fitness status is poor, it indicates that the cell does not develop well, either because the cell is aged, lacks reliability, has an ill-functioning metabolism or is disease prone etc. Earlier in 2021, the research team discovered that fitness status is expressed in proteins called flower proteins. These flower proteins are on the surface of the cell, and they are expressed in two forms, explains Rajan Gogna.

"In one form, they tell the surrounding cells that this cell is doing well. In the other form, they indicate to the surrounding tissue, that this particular cell is not doing well and thus has a bad fitness status. If the cell's fitness status is not great, the cell will get phased out and killed by the surrounding cells." Accurate prediction of serious infection

Especially helpful in cases of the early phase of COVID-19 illness, the flower protein expression could accurately predict hospitalization or…
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