Berry good news: newly discovered compound from blueberries could treat inflammatory disorders: Scientists show how a polyphenolic compound derived from blueberry can treat inflammatory bowel disease

www.sciencedaily.com
3 min read
difficult
Inflammatory bowel disease (IBD), caused by chronic inflammation in the digestive tract linings, can be debilitating and life threatening. Therapeutic options include suppression of immune response, but treatments leading to complete cure of IBD are still not available. Recently, a team of researchers has discovered a polyphenolic compound derived from blueberry that shows remarkable immunosuppressive effects and can be useful in treating IBD.
Various plants and their products are known to contain "bioactive" ingredients that can alleviate human diseases. These "phytocompounds" often contain restorative biological properties such as anti-cancerous, antioxidant, and anti-inflammatory effects. Thus, understanding how they interact with the body can lead to potential treatment strategies against major immune disorders.

A team of researchers at Tokyo University of Science, led by Prof Chiharu Nishiyama, has been working this direction for the past several years, to identify novel active components in functional foods and understand their effects on the body. Their efforts have now led to success: In their latest study, published in The FASEB Journal, the scientists identified a polyphenolic compound called "pterostilbene" (PSB) with strong immunosuppressive properties -- making it a potential therapeutic option for chronic inflammatory diseases, including inflammatory bowel disease (IBD). This compound is very similar to another phytocompound known to have important medicinal effects, called "resveratrol" (RSV). Dr Takuya Yashiro, corresponding author of this report, explains the idea that prompted their research, "RSV, a…
Read full article