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Cross-coupling ketones: Adding flexibility to the synthetic chemistry toolbox

phys.org
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fairly difficult
Researchers have published a paper describing, for the first time, the use of ketones as alkyl cross-coupling synthons.
Researchers from Prof. Martin's group at ICIQ have published a paper in Nature Communications describing, for the first time, the use of ketones as alkyl cross-coupling synthons. Credit: ICIQ



For Xin-Yang Lv and Dr. Roman Abrams, researchers in Prof. Martin's group at the Institute for Chemical Research of Catalonia (ICIQ), keeping up with scientific literature is a source of inspiration for the development of new synthetic methodologies. Taking a recent publication one step further, the scientists in Prof. Martín's group have devised a new strategy that facilitates the creation of organic molecules of pharmacological interest. The method has been published in the open-access journal Nature Communications.

The strategy developed by the Martin group makes ketones available to chemists to be used as alkyl cross-coupling synthons. "This method…
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