Gastroenterology / General Gastroenterology

Fully Automated Capsule Endoscopy Feasible for Gastric Exams

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Minimally invasive, magnetically controlled capsule comparable to conventional endoscopy
A fully automated magnetically controlled capsule endoscopy (FAMCE) was found to be comparable to conventional transoral gastroscopy for gastric examination and lesion detection in a prospective feasibility study conducted at two centers in China.

FAMCE was used to image the stomach and small bowel of 114 patients and detected 100% of gastric anatomical structures (95% CI 99.3-100%), reported Xia Xie, MD, of Second Affiliated Hospital of the Third Military Medical University in Chongqing, and colleagues.

As shown in their study in The Lancet Gastroenterology and Hepatology, the number of missed lesions was five (four cases of gastritis and one polyp) with FAMCE, compared with 16 (12 cases of gastritis, one polyp, one fundal xanthoma, and two antral erosions) with conventional gastroscopy. Furthermore, there was no evidence of capsule retention or serious adverse events associated with FAMCE, the researchers said.

"Therefore, FAMCE is an effective method that can be used in the examination of the gastrointestinal tract," the team wrote.

Xie and co-authors explained that while conventional gastroscopy remains the gold standard for detecting gastric pathologies, some patients may not be able to tolerate the cardiovascular stress associated with the procedure. FAMCE is less invasive, with a magnet used to control the position of a video capsule swallowed by the patient.

Hand-held and robot-assisted magnetically controlled endoscopy techniques have been used for gastric exams, but each have their downsides, the investigators continued. For example, the need for skilled operators for hand-held procedures, and the size and cost of robotic devices, as well as the reliance on an operator to control capsule endoscopy…
Mike Bassett
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