Liraglutide combined with endoscopic bariatric therapy can provide weight loss on par with bariatric surgery alone, raising the question of whether the GLP-1 RAs might one day replace surgery.

Use of a GLP-1 RA before bariatric surgery is likely safe, but unlikely to boost weight loss.

"Even those who had regained some slight weight still had 18% weight loss after on average, 4.5 years, with a standard commercial weight management program." No one took antiobesity drugs or had surgery.

Bariatric surgery may enable peripheral nerve regeneration, making it an effective treatment for individuals with obesity at risk of diabetes and peripheral neuropathy, says a researcher.

Most Americans' views about bariatric surgery are colored by stigmas that could deter those who qualify from pursuing it.

Using a double tube for the drainage element allows the vacuum to be in place for a longer time. The technique has good results and reduces patients' time under therapy.

Administration of semaglutide before metabolic and bariatric surgery does not confer benefits for overall weight loss, according to a recent retrospective study.

Weight loss after bariatric surgery didn't appear to provide mental health benefits in adolescents with severe obesity, found a large long-term Swedish observational study.

2023 highlights included new FDA approvals, more drugs in development, and a pivot away from BMI

Weight loss before laparoscopic sleeve gastrectomy or Roux-en-Y gastric bypass does not improve surgical outcomes, except in select cases.

The rate of this disorder was found to be 2.5 times higher among those who had gastric bypass surgery compared with a control group.

Men and women with severe obesity who had one of four types of bariatric surgery had better survival up to 40 years after than peers without surgery, but those aged 18-34 had a higher risk of suicide.

Real-world data show endoscopic sleeve gastroplasty is safe and leads to significant and sustained weight loss, even in patients with class III obesity.

Those who discontinued the "twincretin" drug after 36 weeks regained weight but still maintained some weight loss at 1 year.

"Professional guidelines and increasing data support bariatric surgery for patients beginning at BMI 30…. Now it needs to happen in the real world," says the outgoing ASMBS president.

While Roux-en-Y gastric bypass complications are higher for all, minorities show higher rates of post-operative hospitalizations, mortality.

CagriSema (cagrilintide plus semaglutide) led to weight loss 'of a magnitude not previously reported with pharmacotherapies in type 2 diabetes,' plus improved CGM measures, in a phase 2 trial.

Lifestyle changes result in the least weight loss and may be safest, while surgery provides the most weight loss and has the greatest risk.

More children in the US are becoming afflicted with severe obesity, with a body mass index 20% higher than the marker for obesity, according to a report in JAMA Pediatrics.

In individuals with obesity, even those aged 65-75 years of age, bariatric surgery can reduce long-term cardiovascular events, such as heart failure, stroke, and myocardial infarction.