Initiating biologic therapy early in order to achieve transmural healing led to better long-term outcomes in patients with Crohn's disease.

Newer agents also associated with lower VTE risk versus non-advanced treatments

In the treatment of psoriasis, preliminary evidence supports the hypothesis that IL-23 inhibitors are capable of extended remissions and protection against PsA relative to other biologics.

Artificial photosynthesis is being developed that would provide a carbon and energy source and allow plants to grow without the benefit of direct sunlight, according to researchers.

Catalent, the global leader in enabling biopharma, cell, gene and consumer health partners to optimize development, launch, and supply of better patient treatments across multiple modalities, today announced that it has increased cold chain packaging capabilities at its Philadelphia facility to support increased demand for the distribution of biologic drugs, and advanced cell and gene therapies.

Elephant seals that have been tagged for biological studies are providing unexpected data about the marine heatwave known as the North Pacific Blob, which continued from 2013 to 2015.

Greater efficacy and fewer infusion reactions were seen with methotrexate-pegloticase combination than pegloticase alone in the placebo-controlled MIRROR trial.

Treatment with the interleukin-12/23 inhibitor ustekinumab or interleukin-23 inhibitors was linked to a lower risk of developing psoriatic arthritis compared with tumor necrosis factor inhibitors.

Patients with GPA completely weaned off glucocorticoids were four times as likely to flare compared with those kept on a low dose, though these flares were minor.

Injectable biologic was approved as adjuvant therapy to inhaled medications.

Key eligibility criteria for both trials included adults or adolescents with a diagnosis of AD as defined by the AAD consensus criteria, for at least 1 year prior to screening.

Offering talimogene laherparepvec before surgery compared with surgery alone could improve event-free as well as overall survival in patients with advanced resectable melanoma, a new analysis suggests.

Japanese drugmaker Eisai and US biotech firm Biogen said on Tuesday that Chinese authorities have given priority review status to lecanemab, their jointly developed Alzheimer's disease treatment drug.

All organisms have two photoreceptors that make the moon's role in setting the body clocks just as important as that of the sun, according to new research.

Black and Hispanic children living in urban settings benefited from biologic therapy

Nektar Therapeutics on Monday sued Eli Lilly, accusing the US drugmaker of undermining the prospects for a drug the companies were developing together for various autoimmune diseases.

The results "support the involvement of type 2 cytokines in driving PN disease pathogenesis and the targeting of the IL-4/IL-13 axis as a novel therapeutic paradigm" for PN, the authors write.

With no biomarkers to say who can safely delay dual therapy, an editorialist said that two checkpoint inhibitors in the first line might be "prudent."

The results are from a large cohort study that estimated the 6-month rate of infections among children with psoriasis who started treatment with ustekinumab, etanercept, or methotrexate.

Experts remain divided on the value of discarded cancer drugs but agree that 'we all are chipping away at this monster of cancer care costs.'