A type of nanoparticle called a metal organic framework (MOF) could be used to deliver vaccines and act as an adjuvant. MIT researchers find these particles provoke a strong immune response by activating the innate immune system through cell proteins called toll-like receptors.

Dr. Jason Bara, a professor in the University of Alabama College of Engineering, leads a team working to improve methods to recycle the plastics we interact with daily.

Imidazole dipeptides (IDPs), which are abundant in meat and fish, are substances produced in the bodies of various animals, including humans, and have been reported to be effective in relieving fatigue and preventing dementia. However, the physiological mechanism by which IDPs exhibit these activities had not been previously determined.

Hydrothermal liquefaction provides a straightforward approach to producing SAF, yet there's nitrogen in the upgraded biocrude, and it has to come out.  Meanwhile, bad news, nitrogen in hydrotreated biocrude consists of a large variety of nitrogenated compounds: Amides and amines, but also non-basic and more refractory indoles, pyridines, pyrimidines, imidazole. Good news, Adsorptive De-Nitrogenation is […]

Fuel cells often fall short when it comes to operating at temperatures beyond 100 degrees Celsius owing to their dependence on water as a proton conduction medium. To overcome this issue, a team of researchers designed a new hydrogen-bonded starburst-shaped metal complex consisting of ruthenium (III) ion and six imidazole-imidazolate groups. The resulting single molecular crystal shows excellent proton conductivity…

As the world is moving towards more environment-friendly and sustainable sources of energy, fuel cells are receiving a lot of attention. The main advantage of fuel cells is that they use hydrogen, a clean fuel, and produce only water as a by-product while generating electricity. This new and clean source of electricity could replace conventional lithium-ion batteries, which currently power all modern electronic…

Development of vaccines against SARS-CoV-2 has been rapid, but the rise of variants forces scientists to frequently modify treatments. Ideally, therapies would target mutation-resistant viral proteins, but this has proven difficult. Researchers reporting in ACS Central Science, however, have now developed a system that directly targets and degrades the viral RNA genome, reducing infection in mice. The method could…

Researchers at the University of Alabama have developed a way of more efficiently and effectively recycling polymers.

Contact allergy to topical antifungal antibiotics often shows up as foot dermatitis and usually involves more than one fungal agent, researchers in Portugal report.

These key building blocks of life were found in space rocks, scientists confirm.

Lawmakers think they can stem the flow of illicit fentanyl and its analogs into our country by seizing the assets of organizations trafficking the drug and its precursors. If that approach worked, organized crime would be a relic of the past. What they don't understand is that even worse, that approach may make the nitazene crisis arrive ahead of schedule.

Chemists at the Ural Federal University have created a sensor for determining the pH of human saliva. This is a fluorophore with strong and stable emission, which picks up the smallest fluctuations in the pH in biological fluids. The analysis is performed using microdoses of the substance and a spectrometer, in which the substance is irradiated with a special lamp. The pH data appears in 5-7 seconds. The first…

When oil contaminates water, it creates a film that reduces oxygen levels and introduces toxic substances. This can lead to the death of aquatic plants and animals, contaminate soil, and ultimately threaten human health.

MIT engineers discovered that when the aluminum in soda cans is purified and mixed with seawater, the solution produces hydrogen — which can power an engine or fuel cell without generating carbon emissions. The reaction can be sped up by adding caffeine.

Seawater, which comprises more than 95% of the Earth's water, could become a key resource in the sustainable production of clean hydrogen fuel with use of water-splitting catalysts developed by a KAUST-led team.

In aerobic organisms, reactive oxygen species (ROS), such as hydroxide (OH), singlet oxygen (1O2), hydrogen peroxide (H2O2), and superoxide (O2–) ions are produced during aerobic respiration, which causes serious oxidative damage to biomolecules in the body. Hence, the removal of ROS, particularly O2–, is of primary importance as it reacts with H+ to produce other toxic ROS species like H2O2 and OH.

Systematic measurements of the interactions between proteins found on the surfaces of human leukocytes provides a global view of the way that immune cells are dynamically connected by receptors.

The tiny microbes inside us exist in a fermenting soup and the drugs they produce to survive can alter health

Article URL: https://www.science.org/content/blog-post/these-are-real-compounds Comments URL: https://news.ycombinator.com/item?id=30781345 Points: 2 # Comments: 0

SARS-CoV-2 neutralizing antibodies are readily detected with a biosensor.