The top 3 things you should know to start your day.

Contrary to hints from previous research, there is no apparent venous or arterial thrombotic risk associated with higher lipoprotein(a) levels, a new study suggests.

Alternating on and off the lifesaving drugs in unblinded personal trials improved uptake, compared with usual care, in a small study, setting the stage for a larger feasibility trial.

Lower LDL cholesterol levels were not a predictor of intracranial hemorrhage events in a new analysis of the TST trial.

Certain polyunsaturated fatty acids (PUFAs) may have a favorable effect on disease progression and survival for patients with amyotrophic lateral sclerosis.

Switching from one healthy weight loss diet to another did not overcome the typical weight loss plateau at 6 months in individuals with overweight and obesity.

The median age of death from homozygous familial hypercholesterolemia is just 32 years, with many patients having had poor lipid control, shows registry data described by one expert as "terrifying."

The relation is relatively modest but strongly argues for increased testing of Lp(a) and adding atrial fibrillation as a secondary outcome to ongoing trials, experts say.

For doctors with patients who don't know they're taking too much of a medication, "you wonder whether the drug is causing the health problems, and it's a symptom of the wrong medication."

Starting lipid-lowering treatment earlier in life may reduce cardiovascular risk in patients with familial hypercholesterolemia vs those who do not, a meta-analysis suggests.

Statin users need not limit exercise out of concern that the drugs will worsen normal muscle pain or fatigue, a controlled study suggests.

A new Cholesterol Trialists Collaboration meta-analysis shows that in 14 of 15 people who experience muscle pain or weakness when taking a statin, symptoms are not related to treatment.

Rosuvastatin, simvastatin, and atorvastatin were most effective in reducing levels of non-high-density-lipoprotein cholesterol in people with diabetes in a network meta-analysis of 42 clinical trials.

The prevalence of elevated low-density lipoprotein cholesterol has declined recently, but millions of Americans still have levels for which treatment is recommended or should be considered and many remain untreated.

While cholesterol levels in American adults have improved overall in the past decade, disparities in control have emerged, in a new analysis.

While the overall life expectancy increased in both men and women, researchers at the Annals of Internal Medicine found that disparities persisted when race was factored in.

While a Korean study shows reduction in diabetic retinopathy progression by 11% with fenofibrate plus statin compared with statin alone, some reservations remain over wider use.

An observational study shows statins are linked to a lower risk of age-related parkinsonism that may be partially mediated by less severe intracranial atherosclerosis.

A daily 40-mg dose of atorvastatin for 12 months significantly cut incident cardiac dysfunction in patients with lymphoma receiving anthracycline treatment.

Observational data suggest that use of statins after intracerebral hemorrhage is linked to lower risk for recurrent stroke. Researchers call for a randomized trial of statins in these patients.