Broad Institute

The HHS Secretary fields criticism of his long-held autism beliefs.

Results strongest in those with more advanced chronic kidney disease

MIT Professor Xiao Wang's research is focused on developing tools that pinpoint where in a cell different types of messenger RNA are translated into proteins — information that can offer insight into how cells control their fate and what goes wrong in disease.

Inspired by the jets of water squids use to propel themselves, an MIT-led team developed an ingestible capsule that releases drugs directly into the lining of the stomach or other organs of the digestive tract.

MIT researchers developed theoretical foundations for methods that could identify the best way to aggregate genes into modules and efficiently learn the underlying cause-and-effect relationships among them. This approach holds promise for investigating the mechanisms of diseases and identifying new drug targets.

The interactive segmentation tool "ScribblePrompt" allows users to scribble, click, and use bounding boxes to delineate anatomical structures in biomedical images. This manual annotation algorithm was trained on synthetic data that simulated how humans interact with medical scans.

Mathieu Le Provost, a postdoctoral associate in the MIT Department of Aeronautics and Astronautics, passed away unexpectedly on Tuesday, July 30, 2024 while traveling in France.

Also, eHealth NSW is expanding the Clinical Device Notification Platform to rural and remote areas in Sydney.

The promise of gene therapy looms large for families dealing with rare, genetic disorders

Two bioactive, natural-derived compounds, which show activity at the GLP-1R site, may be orally administered with fewer side effects than their pharmaceutical counterparts.

Humans' closest primate relatives lost their tails long ago, but exactly how has remained a mystery. A breakthrough in genetic research may finally offer...

A Stanford Medicine study found that metformin, a commonly prescribed diabetes drug associated with moderate weight loss, stimulates production of lac-phe, a molecule abundant after exercise. An "anti-hunger" molecule produced after vigorous exercise is responsible for the moderate weight loss caus

Millions of years ago, our ancient ancestors, the apes, lost their tails. A new study shows how (and hints at why).

Blood cells make up the majority of cells in the human body. They perform critical functions and their dysfunction is implicated in many important human diseases, from anemias to blood cancers like leukemia. The many types of blood cells include red blood cells that carry oxygen, platelets that promote clotting, as well as the myriad types of immune cells that protect our bodies from threats such as viruses and…

Will an AI discover the next miracle cure?

The projects are poised to offer unprecedented insights into human genetic diversity and improve treatment of disease.

A deep-learning algorithm helped identify new compounds that are effective against antibiotic-resistant infections in mice, opening the door to AI-guided drug discovery

Researchers used an algorithm to scour databases of bacterial genomes for never-before-seen CRISPR systems.

A new atlas of the human brain could help explain abilities like language – and vulnerabilities, like Alzheimer's disease.

The Rett Syndrome Research Trust (RSRT) is delighted to announce the successful conclusion of the inaugural Rett Syndrome Genetic Medicines Summit, held...