Expression Vector

A research group led by Prof. Shao Zhen from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences (CAS) and the collaborators charted a high-resolution roadmap for the process of pancreatic β cell regeneration by in vivo transdifferentiation from adult acinar cells using single-cell RNA sequencing (scRNA-seq) technology. The study was published in Science Advances.

A metabolite screen of pancreatic cells shows that pancreatic cancer cells metabolize uridine-derived ribose via UPP1, supporting redox balance, survival and proliferation.

In this free webinar, learn about Escherichia coli (E. coli)'s position as the most popular host for recombinant protein production. Attendees will be...

'It is hard to believe that Dr. Ladapo actually issued that statement,' said vaccine expert

Two lineages of influenza B viruses (IBV) co-circulating in human beings have been posing a significant public health burden worldwide. A substantial number of broadly neutralizing antibodies (bnAbs) have been identified targeting conserved epitopes on hemagglutinin (HA) stem domain, posing great interest for universal influenza vaccine development. Various strategies to design immunogens that selectively present…

edit: Changed title from "Postmortem on RatVac" for clarity.

Experiments in mice show that designed epigenome editors that contain domains of transcriptional repressors can enable stable epigenetic silencing of Pcsk9, a gene with a role in cholesterol homeostasis, without inducing DNA breaks.

Significant decrease in rate of photoreceptor loss in two randomized trials

The COVID-19 shots are turning out to be more of a time bomb than ever imagined. This new ...

In the Drosophila central-pattern-generating neural network, a mechanism for network desynchronization relying on weak electrical synapses and specific excitability dynamics of the coupled neurons translates unpatterned premotor input into stereotyped neuronal firing with fixed sequences of cell activation, ensuring stable wingbeat power.