Nuclear Magnetic Resonance

Individuals' metabolomic marker profiles may predict the onset of inflammatory bowel disease a decade in advance, underlining the systemic nature of the disease.

Clare Grey, Royal Society Research Professor and the Geoffrey Moorhouse-Gibson Professor of Chemistry at Cambridge University, delivered the 2024 Dresselhaus Lecture at MIT on understanding battery function.

They are found in everyday tech devices, and China controls a huge part of the market.

A research team led by Prof. Wang Pengfei from Xi'an Institute of Optics and Precision Mechanics (XIOPM) of the Chinese Academy of Sciences revealed the relationship between F/O ratio and the structure of fluorophosphate glass through conducting comprehensive research on Raman spectroscopy and nuclear magnetic resonance (NMR) spectroscopy.

Natural products have unique chemical structures and biological activities and can play a pivotal role in advancing pharmaceutical science. In a study published in Heliyon, researchers from Shinshu University have discovered inaoside A, an antioxidant derived from Laetiporus cremeiporus mushrooms. This breakthrough sheds light on the potential of mushrooms as a source of therapeutic bioactive compounds.

A study conducted at the Center for Research, Education and Innovation in Vitreous Materials (CeRTEV) in São Carlos, São Paulo state, Brazil, shows for the first time that including niobium oxide (Nb2O5) in silicate glass results in silica network polymerization, which increases bond density and connectivity, enhancing the mechanical and thermal stability of specialty glass.

MIT chemists have gained insight into how Tau tangles form in the brains of people with Alzheimer's disease. They also identified a potential target for drugs that could interfere with tangle formation.

In chemistry, a molecule or ion is said to be chiral if it cannot be superposed on to its mirror image by any combination of rotations, translations, or conformational changes. A chiral molecule or ion exists in two forms, called enantiomers, that are mirror images of each other; they are often distinguished as either 'right-handed' or 'left-handed' by their absolute configuration. Enantiomers exhibit similar…

GDF15 treatment in mice counteracts compensatory reductions in energy expenditure, resulting in greater weight loss and reductions in non-alcoholic fatty liver disease compared to caloric restriction alone.

Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I displays peptide fragments of proteins from within the cell on the cell surface, "presenting" them to the immune system, which is constantly scanning the body for foreign or toxic antigens.

Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers at the University of Zurich and the company Spexis have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.

Biodegradation of plastic at low temperatures can save money and energy. Researchers have discovered microbial strains in the high altitudes of the Alps and in the polar regions that can break down biodegradable plastics at temperatures as low as 15°C (59°F). These microbes, found in the plastisp

Many of the biological materials that researchers are most interested in studying, including those associated with major diseases, don't lend themselves to the conventional methods that researchers typically use to probe a material's structure and chemistry.

For two decades, physicists have tried to directly manipulate the spin of electrons in 2D materials like graphene. Doing so could spark key advances in the burgeoning world of 2D electronics, a field where super-fast, small and flexible electronic devices carry out computations based on quantum mechanics.

Magnesium diboride (MgB2) is a low-cost, non-toxic superconductor used in field magnets, electric motors, and generators. However, producing nanoscale boron (B) particles to fabricate MgB2 is expensive. Researchers recently tackled this issue by using high-energy ultra-sonication in 2-propanol, a highly viscous solvent, to produce impurity-free, nm-sized B particles. The approach is cost-effective and enables…

A team of chemists affiliated with several institutions in Germany has found that using a ball mill can speed up sublimation needed for testing gas interactions. In their study, reported in the journal Chem, the group tested the use of a ball mill to see how it would impact sublimation.

A Knowledge Graph of Common Chemical Names to their Molecular Definition - GitHub - Global-Chem/global-chem: A Knowledge Graph of Common Chemical Names to their Molecular Definition

Article URL: https://www.science.org/content/blog-post/bullvalene-antibiotics-all-things Comments URL: https://news.ycombinator.com/item?id=35472401 Points: 1 # Comments: 0

If serine racemase is the magician that for decades disguised its trick—inverting an amino acid to assist learning and memory but also levitate risks of Alzheimer's and stroke—chemists just snuck a high-res camera behind the curtain.

A team of undergraduate and graduate chemistry students in Jennifer Hines' lab at Ohio University recently uncovered a new class of compounds that can target RNA and disrupt its function. This discovery identified a chemical scaffold that could ultimately be used in the development of RNA-targeted medicines to treat bacterial and viral infections, as well as cancer and metabolic diseases.