Gram-Negative

The microbiome is a gut-wrenching mystery. One day, it's the key to immortality; the next, it's just along for the ride. If you've ever been told to fear sweeteners, shun sugar, and bow to fermented foods lest you destroy your delicate microbial overlords, it turns out what we think we know is much like a juice cleanse— fleeting, overhyped, and occasionally full of crap.

Evidence supports narrow indication for intervertebral injections of condoliase, advisors say

The guideline covers a range of clinical topics, including prophylaxis and antimicrobial stewardship, but there is a lack of high-quality evidence on many issues.

Investigators of the seven-country BALANCE trial said cutting duration to 7 days could slash costs and reduce harms and may reduce antibiotic resistance.

Compared with other methods, urine Gram stain moderately predicted gram-negative bacteria but added little value to UTI diagnosis in the ED, raising questions about its clinical utility.

A study in Nature reveals that our understanding of the balance of pro- and anti-inflammatory forces extends beyond immune cells to a surprising player: the vagus nerve. This wandering nerve, connecting our body and brain, influences our immune response in ways previously unknown.

Scientists have figured out a whole new way to cut the legs out from underneath drug-resistant bacterial infections.

Cefepime-enmetazobactam beat piperacillin-tazobactam in phase III study

Traditional antibiotics drive bacteria toward drug resistance, so scientists are looking to viruses, CRISPR, designer molecules and protein swords for better superbug treatments

RUDN University chemists have improved the effectiveness of antibacterial chitosan films used in medicine and the food industry, by adding iron and a new chitin derivative to chitin nanoparticles. The results were published in the journal BioTech.

In a cross-collaboration between researchers at the University of Colorado, MIT, and the NASA Ames Research Center, researchers studied how to prevent...

Climate change may be impacting our immune systems, a study from the University of Bergen, Norway, shows. This research brings into focus the intricate interplay between environmental factors, microbial communities and their potential impact on human health.

Examples of infections tied to gram-negative bacteria include pneumonia, bloodstream infections, wound-site infections and meningitis, according to the Centers for Disease Control and Prevention.

A new analysis shows that infectious bacteria exposed to the antibiotic albicidin rapidly develop up to a 1,000-fold increase in resistance via a gene amplification mechanism. Mareike Saathoff of Freie Universität Berlin, Germany, and colleagues present these findings in the open access journal PLOS Biology.

A recent article in USA Today proclaimed that we are *this* far away from no longer having working antibiotics, a cataclysmic development that would pose "an existential threat for modern medicine." Is this really true? Let's ask Dr. David Shlaes, one of the foremost experts in the world of antimicrobial science.

Liz Sockett recounts lessons learned by getting to know Bdellovibrio bacteriovorus, a single-celled predator that invades and kills Gram-negative bacteria from within.

Deaths from antibiotic-resistant bacteria, also known as superbugs, have been on the rise globally, and health regulators have called for the development of ...

The CDC warned against using EzriCare eye drops after they were linked to drug-resistant bacterial infections, vision loss, and death. Researchers have now detailed a case of a corneal ulcer caused by Pseudomonas aeruginosa, which was traced back to contaminated eye drops. Although the product has b

There aren't enough new antibiotics in the pipeline, the World Health Organization (WHO) is warning, to deal with deadly pathogens; "antibiotic resistance" is a big concern in medicine today.

In a study published in the journal Science China Life Sciences, Miichthys miiuy in teleost was taken as the research object to explore whether lncRNA can play a regulatory role in the process of teleost resisting susceptible pathogenic Vibrio infection. And the researchers found that the expression of lncRNA TARL was up-regulated in the spleen tissue of M. miiuy stimulated by LPS.