Arene Substitution Pattern

The Chirik Group at the Princeton Department of Chemistry is chipping away at one of the great challenges of metal-catalyzed C–H functionalization with a new method that uses a cobalt catalyst to differentiate between bonds in fluoroarenes, functionalizing them based on their intrinsic electronic properties.

Ephedra-type alkaloids, a class of naturally occurring compounds derived from plants in the genus Ephedra, have long held interest in the pharmaceutical industry due to their stimulant and airway widening effects. These alkaloids are used for the treatment of conditions such as asthma and low blood pressure.

Meta announced that Instagram Threads would join the fediverse, which is more grounded in reality than the metaverse — but arguably more confusing

Molecules offer enormous capacity for information storage. Here, the authors show that information can be encoded into molecules with sequences of paramagnetic lanthanide ions, and decoded using nuclear magnetic resonance spectroscopy.

Helicenes are organic molecules that gained widespread popularity due to their unique helical π-conjugated molecular structure, where the benzene rings are ortho-fused, resulting in excellent chiroptical properties such as circularly polarized luminescence (CPL). The ability to act as a CPL emitter makes helicenes ideal for a wide range of next-generation optoelectronic applications, such as optical information…

Biocatalytic nitration is a promising method for the preparation of nitro compounds. However, few nitration reactions have been developed using biocatalysis due to the lack of native nitrating enzymes and/or the narrow substrate scope of the enzymes.

In chemicals used in agriculture, as well as in pharmaceuticals and a variety of materials, pyridines are often found as so-called functional units that decisively determine the chemical properties of substances. Pyridines belong to the group of ring-shaped carbon-hydrogen (C-H) compounds ("heterocycles"), and they contain a nitrogen atom (N). For chemists, the direct functionalization of the carbon-hydrogen bonds…

From life-saving drugs and synthetic polymers to diverse advanced materials, the products containing organic compounds seem endless, thanks in part to regioselectivity, a feature in chemical reactions where a substituent is selectively added to a specific position of an organic compound. This favors the formation of desired products with specific functionalities.

Article URL: https://en.wikipedia.org/wiki/Xylene Comments URL: https://news.ycombinator.com/item?id=35767760 Points: 1 # Comments: 0

Chief Business Officer Marne Levine announced she will leave Meta after 13 years at the company where she held multiple leadership roles.

Stereochemistry, or the study of spatial arrangements of the atoms in a molecule, is a highly explored subdiscipline of organic chemistry. It has led to the synthesis of numerous chiral compounds—compounds with non-superimposable mirror images or enantiomers—which have found applications in fields ranging from biosensing to nanotechnology and drug delivery.