Radium-223

Combining radium-223 with enzalutamide offered a survival benefit in metastatic castration-resistant prostate cancer, but experts questioned its relevance in a shifting treatment landscape.

Scientists need a better understanding of the chemistry of radium to be able to target the isotope radium-223 (Ra-223) to cancer cells. Once delivered, Ra-223 can destroy those cells with alpha particles, a type of radiation.

/PRNewswire-PRWeb/ -- CRO and Biotech Discuss Advancements in...

Hazards for radiographic PFS, OS reduced by 31% with enzalutamide plus Ra-223

The agency has approved lutetium Lu 177 vipivotide tetraxetan (Pluvicto) for treatment and gallium Ga 68 gozetotide (Locametz) as a diagnostic for use with PET imaging.

Adding radium-223 to estrogen therapy to target bone metastases may provide slight gain but comes with more adverse events. The study was published as a preprint and has not yet been peer reviewed.

Researchers at Oak Ridge National Laboratory explored radium's chemistry to advance cancer treatments using ionizing radiation. Their results appear in Chemical Communications.

Does francium have any practical uses?

Orteronel misses mark in metastatic hormone-sensitive prostate cancer, after failures in mCRPC

Median OS of 15.5 months, PFS of 7.9 months with Ac-225-PSMA in heavily treated patients

Several studies in prostate cancer have recently opened their doors. Perhaps one of your patients is eligible to take part?