Journal of Extracellular Vesicles

A study has demonstrated that nano-sized vesicles released by red blood cells are a viable platform for delivering immunotherapeutic RNA molecules to suppress breast cancer growth and metastasis. The study successfully delivered RIG-I-activating RNAs using small, lipid membrane-bound particles released by red blood cells, called red blood cell extracellular vesicles (RBCEVs), to suppress cancer progression. The…

A team of uOttawa Faculty of Medicine researchers have developed a path to a biomanufacturing process that could potentially transform how Canada generates immunotherapeutic materials—specifically natural killer cells and extracellular vesicles (EVs)—to fuel tomorrow's novel cancer treatments.

In a study recently published in the Journal of Extracellular Vesicles, researchers from Kanazawa University use high-speed microscopy to capture the dynamics of nanosized sacs released from cells.

A new study by the University of Barcelona could drive the design of future strategies to regenerate damaged brain areas in neurodegenerative diseases. The study emphasizes the role of neuron-derived extracellular vesicles in the processes that modulate synaptic plasticity and neuronal signaling pathways. In addition, the results outline a new scenario for using these extracellular vesicles derived from healthy…

Biophysicists from Skoltech, MIPT and their colleagues from the company Prostagnost have created a new technology for isolating extracellular vesicles (EV) from biological fluids. Studying vesicles is essential for the diagnosis and treatment of various diseases, including cancer. The new technique not only outperforms methods known to date in purity and yield of EVs, but also is simple, fast, inexpensive and can…