Max Delbrück

The molecular tool CRISPR-Cas9 can be used to treat inherited blood disorders, but this may cause unintended genetic alterations. A team led by MDC researchers Klaus Rajewsky and Van Trung Chu has now presented an approach in Science Advances that minimizes such adverse consequences.

Researchers are running trials on how hormone therapies affect trans people that will also benefit healthcare for the wider population

The little skate's dance on the ocean floor is graceful: Its massive frontal fins undulate as it skims beneath a layer of sand. With its mottled sand-colored camouflage, the animal is easy to miss.

Blog posts about GNU Guix.

The American Physical Society recognized a number of MIT affiliates with honors and prizes for their contributions to physics. Honorees include Arup Chakraborty, Lina Necib, Ronald Fernando Garcia Ruiz, Yuan Cao, Alina Kononov, Elliott H. Lieb, and Haocun Yu.

Letters respond to Siddhartha Mukherjee's piece about cancer, Masha Gessen's essay on Gaza and the Holocaust, and Charles Duhigg's piece about Microsoft and OpenAI.

Chemotherapy as a treatment for cancer is one of the major medical success stories of the 20th century, but it's far from perfect. Anyone who has been through chemotherapy or who has had a friend or loved one go through it will be familiar with its many side effects: hair loss, nausea, weakened immune system, and even infertility and nerve damage.

Researchers at the Centre for Genomic Regulation (CRG) in Barcelona and the Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin have revealed how cells accelerate changes to their identity, a process known as cell fate conversion.

Scientists studying gene activity data of the early human embryo have discovered an overlooked type of cell that self-destructs within days of forming, as part of a quality control process to protect the developing fetus. The findings give insights on what happens at the very first stages of life after fertilization which could in the future help improve IVF or regenerative medicine treatments.

Every biologist knows that small structures can sometimes have a big impact: Millions of signaling molecules, hormones, and other biomolecules are bustling around in our cells and tissues, playing a leading role in many of the key processes occurring in our bodies. Yet despite this knowledge, biologists and physicians long ignored a particular class of proteins—their assumption being that because the proteins were…

Cephalopods like octopuses, squids and cuttlefish are highly intelligent animals with complex nervous systems. In Science Advances, a team led by Nikolaus Rajewsky of the Max Delbrück Center has now shown that their evolution is linked to a dramatic expansion of their microRNA repertoire.

How the Rockefeller Foundation revolutionized biology.

The most comprehensive cell "atlas" of the developing human heart to date was crafted using cutting-edge technology and includes never-before-seen cell types.

The human immune system is constantly fending off a wide range of invaders—a feat that requires a diverse array of cellular troops and molecular weaponry. Although a great deal is already known about immune defense cells and the strategies they employ, many molecular details have remained elusive.

Since the outbreak of COVID-19, scientists have been exploring the development of mucosal vaccines that can be delivered through the nasal route. Recently, researchers in Berlin have successfully created a live attenuated vaccine for the nose. In a recent study, they detail the unique immune respons

Octopuses and their cephalopod relatives are exceptionally intelligent invertebrates with a highly complex nervous system.

Cephalopods like octopuses, squids and cuttlefish are highly intelligent animals with complex nervous systems. In "Science Advances", a team led by Nikolaus Rajewsky of the Max Delbrück Center has now shown that their evolution is linked to a dramatic expansion of their microRNA repertoire.

Here's a look at past winners of the Nobel Prize in Medicine.

A team of researchers from the lab of Prof. Stein Aerts (VIB-KU Leuven) presents Nova-ST, a new spatial transcriptomics technique that promises to transform gene expression profiling in tissue samples. Nova-ST will make large-scale, high-resolution spatial tissue analysis more accessible and affordable, offering significant benefits for researchers. The research was published in Cell Reports Methods.

People who owned black-and-white television sets until the 1980s didn't know what they were missing until they got a color TV.