Anwain or Anwain Clan is a geographic area in Nigeria and also the people who live in it. Anwain Clan is one of the thirteen clans in Etsakọ land. The geographic area of Anwain is situated in the southern part of Etsakọ West, a local government area of Edo State. It is ward eight among the twelve wards of the Etsakọ local government area. Within Etsakọ West, Anwain is bounded by Ayuele, South Uneme, South Ibie, Ekperi, and Jagbe Clans. It also has boundaries with the clans Uzea and Afuda in the local government areas of Esan-North-East and Esan North Central respectively.