Asparagine-tRNA Ligase

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EC enzyme number
6.1.1.22
Wikipedia creation date
11/17/2007
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Wikipedia opening text
In enzymology, an asparagine-tRNA ligase (EC 6.1.1.22) is an enzyme that catalyzes the chemical reaction ATP + L-asparagine + tRNAAsn ⇌ {\displaystyle \rightleftharpoons } AMP + diphosphate + L-asparaginyl-tRNAAsn The 3 substrates of this enzyme are ATP, L-asparagine, and tRNA(Asn), whereas its 3 products are AMP, diphosphate, and L-asparaginyl-tRNA(Asn). This enzyme belongs to the family of ligases, to be specific those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is L-asparagine:tRNAAsn ligase (AMP-forming). Other names in common use include asparaginyl-tRNA synthetase, asparaginyl-transfer ribonucleate synthetase, asparaginyl transfer RNA synthetase, asparaginyl transfer ribonucleic acid synthetase, asparagyl-transfer RNA synthetase, and asparagine translase. This enzyme participates in alanine and aspartate metabolism and aminoacyl-trna biosynthesis.
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Asparagine-tRNA ligase
EC 6.1.1.22
L-asparagine:tRNAAsn ligase (AMP-forming)
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