Aspartate-Ammonia Ligase

EC enzyme number
Wikipedia creation date
Wikipedia incoming links count
Wikipedia opening text
In enzymology, an aspartate-ammonia ligase (EC is an enzyme that catalyzes the chemical reaction ATP + L-aspartate + NH3 ⇌ {\displaystyle \rightleftharpoons } AMP + diphosphate + L-asparagine The 3 substrates of this enzyme are ATP, L-aspartate, and NH3, whereas its 3 products are AMP, diphosphate, and L-asparagine. This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-ammonia (or amine) ligases (amide synthases). The systematic name of this enzyme class is L-aspartate:ammonia ligase (AMP-forming). Other names in common use include asparagine synthetase, and L-asparagine synthetase. This enzyme participates in 3 metabolic pathways: alanine and aspartate metabolism, cyanoamino acid metabolism, and nitrogen metabolism.
Wikipedia redirect
Aspartate-ammonia ligase
L-aspartate:ammonia ligase (AMP-forming)
Wikipedia URL
MeSH descriptor ID