Pancreatic Cancer

Endocrine gland cancer located in the pancreas
trends
AugustSeptemberOctoberNovemberDecember20210500
alias
pancreas neoplasm
pancreatic neoplasm
pancreatic tumor
malignant neoplasm of tail of pancreas
malignant neoplasm of body of pancreas
Ca tail of pancreas
Ca head of pancreas
Ca body of pancreas
malignant neoplasm of head of pancreas
Neoplasm of Pancreas
Neoplasm of the Pancreas
Tumor of the Pancreas
pancreas neoplasm (disease)
Pancreas Tumor
Tumor of Pancreas
drug used for treatment
Octreotide
Docetaxel
Tamoxifen
Irinotecan
Ifosfamide
Fluorouracil
α-Streptozocin
genetic association
incidence
10 ± 2 cases per 100000 person-years
location
2 ± 1 cases per 100000 person-years
location
media
ICD-9-CM
157.1
157.8
157.0
157.2
NCI Thesaurus ID
C3305
mapping relation type
C3305
exact match
Commons category
Pancreatic cancer
Wikipedia creation date
11/11/2003
Wikipedia incoming links count
Wikipedia opening text
Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass. These cancerous cells have the ability to invade other parts of the body. There are a number of types of pancreatic cancer. The most common, pancreatic adenocarcinoma, accounts for about 85% of cases, and the term "pancreatic cancer" is sometimes used to refer only to that type. These adenocarcinomas start within the part of the pancreas which makes digestive enzymes. Several other types of cancer, which collectively represent the majority of the non-adenocarcinomas, can also arise from these cells. One to two percent of cases of pancreatic cancer are neuroendocrine tumors, which arise from the hormone-producing cells of the pancreas. These are generally less aggressive than pancreatic adenocarcinoma. Signs and symptoms of the most-common form of pancreatic cancer may include yellow skin, abdominal or back pain, unexplained weight loss, light-colored stools, dark urine, and loss of appetite. There are usually no symptoms in the disease's early stages, and symptoms that are specific enough to suggest pancreatic cancer typically do not develop until the disease has reached an advanced stage. By the time of diagnosis, pancreatic cancer has often spread to other parts of the body. Pancreatic cancer rarely occurs before the age of 40, and more than half of cases of pancreatic adenocarcinoma occur in those over 70. Risk factors for pancreatic cancer include tobacco smoking, obesity, diabetes, and certain rare genetic conditions. About 25% of cases are linked to smoking, and 5–10% are linked to inherited genes. Pancreatic cancer is usually diagnosed by a combination of medical imaging techniques such as ultrasound or computed tomography, blood tests, and examination of tissue samples (biopsy). The disease is divided into stages, from early (stage I) to late (stage IV). Screening the general population has not been found to be effective. The risk of developing pancreatic cancer is lower among non-smokers, and people who maintain a healthy weight and limit their consumption of red or processed meat. A smoker's chance of developing the disease decreases if they stop smoking and almost returns to that of the rest of the population after 20 years. Pancreatic cancer can be treated with surgery, radiotherapy, chemotherapy, palliative care, or a combination of these. Treatment options are partly based on the cancer stage. Surgery is the only treatment that can cure pancreatic adenocarcinoma, and may also be done to improve quality of life without the potential for cure. Pain management and medications to improve digestion are sometimes needed. Early palliative care is recommended even for those receiving treatment that aims for a cure. In 2015, pancreatic cancers of all types resulted in 411,600 deaths globally. Pancreatic cancer is the fifth most-common cause of death from cancer in the United Kingdom, and the third most-common in the United States. The disease occurs most often in the developed world, where about 70% of the new cases in 2012 originated. Pancreatic adenocarcinoma typically has a very poor prognosis: after diagnosis, 25% of people survive one year and 5% live for five years. For cancers diagnosed early, the five-year survival rate rises to about 20%. Neuroendocrine cancers have better outcomes; at five years from diagnosis, 65% of those diagnosed are living, though survival varies considerably depending on the type of tumor.
Wikipedia redirect
Cancer of the pancreas
Pancreatic Cancer
Carcinoma of pancreas
Pancreatic carcinoma
Pancreatic malignancy
Pancreatic islet cell neoplasm
Pancreatic islet cell tumors
Pancreatic neoplasms
Carcinoma, pancreatic ductal
Carcinoma pancreas
Pancreas cancer
Exocrine pancreatic cancer
Pancreatic ductal carcinoma
Pancreatic carcinoma, familial
Familial pancreatic carcinoma
Pancreatic intraepithelial neoplasia
Pancreatic neoplasia
Pancreatic cancers
Exocrine cancer
Pancreatic adenoma
Pancreatic adenocarcinoma
Pancreatic ductal adenocarcinoma
Adenocarcinoma of the pancreas
Wikipedia URL
Disease Ontology ID
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Human Phenotype Ontology ID
ICD-10-CM
JSTOR topic ID
Library of Congress authority ID
MedlinePlus ID
MonDO ID
MONDO:0021040
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external links