Do masks not only shield against virus, but also help boost immunity?

www.timesofisrael.com
4 min read
fairly difficult
Unproven hypothesis suggests face coverings expose some wearers to small doses of coronavirus, sparking immune response, but not serious illness
AFP — Could the mask — already seen by many scientists as the most effective shield against COVID-19 — have yet another benefit?

Some researchers now believe that maks expose wearers to smaller, less harmful doses of the virus, which spark an immune response.

This unproven theory suggests that masks could help inoculate people while we wait for a vaccine.

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Non-medical fabric or disposable masks have been recommended across the world, mainly as a way to help stop infected people from spreading the new coronavirus.

While they do not offer full protection, masks may potentially reduce the amount of virus inhaled by a wearer, according to a recent paper published this month in the prestigious New England Journal of Medicine (NEJM).

"We hypothesize that the higher a dose (or inoculum) of virus you get into your body, the more sick you get," one of the authors, Monica Gandhi, a specialist in infectious diseases at the University of California San Francisco, told AFP. "We think that masks reduce that dose of virus that you inhale and, thereby, drive up rates of asymptomatic infection."

Gandhi, director of the UCSF-Gladstone Center for AIDS Research, said that asymptomatic infection was linked to a strong immune response from T lymphocytes — a type of white blood cell — that may act against COVID-19.

"We think masks can act as a sort of 'bridge' to a vaccine by giving us some immunity," she said, adding that researchers were launching several…
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